Tech Transfer Helps Professor Launch Start-Up

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The associate professor credits the tech transfer office for shepherding his start-up.

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portrait of Gevorg Grigoryan in the Life Sciences Center
Associate Professor Gevorg Grigoryan says support from 线上赌场鈥檚 technology transfer office played an important role in the launch of his start-up. (Photo by Eli Burakian 鈥00) 
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, an associate professor of computer science, says support from 线上赌场鈥檚 technology transfer office played an important role in the launch of his start-up, Generate Biomedicines, which just received a $50 million investment from a leading biotech venture capital firm.

骋谤颈驳辞谤测补苍鈥檚&苍产蝉辫; has developed algorithms to extract fundamental insights from protein structural data accumulated worldwide over the past 60 years, and thus to permit the computational design of biological therapies for specific diseases. The process helps researchers develop new medicines in a fraction of the time, says Grigoryan, who is also an adjunct professor of  and .

鈥淲e are thrilled that Gevorg鈥檚 discoveries are attracting the substantial resources needed to advance this important work to the next level,鈥 says , vice provost for research and director of the COBRE Institute for Biomolecular Targeting, which funded some of Grigoryan鈥檚 early work.

鈥淚t is a great testament to the ingenuity and the potential of his approach. It is also such an inspiring model for how excellent research at 线上赌场 translates into social good while creating a positive economic impact,鈥 Madden says. 

In the past year, the technology transfer office鈥攑art of the 线上赌场 Office of Entrepreneurship and Technology Transfer鈥攈as filed more than 100 new patent applications on 线上赌场 inventions, entered into 32 license agreements, and assisted investigators in forming six new companies to commercialize technologies resulting from 线上赌场 research. Tech transfer has also assisted 线上赌场 faculty, staff, students, and community members with more than 400 agreements relating to material transfers and relationships with industry.

Grigoyan says the office provided vital assistance when he first started thinking about how to commercialize his research and took the lead in negotiating the agreement that was essential to the launch of Generate Biomedicines.

鈥淚 did get lucky in lots of ways, but one of the important ways was that I got fantastic feedback from everyone at tech transfer,鈥 he says.

Fortunately, says , director of the technology transfer office, Grigoryan sought advice on patent rights early on.

鈥淚t was critical that Gevorg disclosed his invention to our office so that we could file for patent protection before he published or shared his research, which could have blocked its patentability,鈥 she says.

The licensing and business development managers in the office also connected him with the entrepreneurial ecosystem at 线上赌场, Grigoryan says, where he found support from the , the , and alumni entrepreneurial networks. A connection at MIT, where he had earned his PhD, ultimately that led to the co-founding of Generate with Flagship Pioneering, a venture creation firm that counts among its start-ups Moderna, which is developing a vaccine for the novel coronavirus.

When the time came to negotiate a deal with Flagship, tech transfer stepped up again, Grigoryan says. By managing the legal and business issues, the tech transfer office allowed him to focus on the science and avoid conflicts of interests as both a 线上赌场 faculty member and a principle in a startup licensing the intellectual property, he says.

鈥淭hey allowed me to be disconnected from that process.鈥

Federal law requires that institutions transfer discoveries resulting from federally funded research to the commercial marketplace. It is a social compact which benefits society, but also recognizes that the institution and the researchers are entitled to benefit from the intellectual property, Rosenfield says.

鈥溝呱隙某 is in the business of education, disseminating knowledge, creating new knowledge. We鈥檙e not in the business of getting regulatory approval, manufacturing, distribution, or marketing,鈥 Rosenfield says. 鈥淪o, if we want this knowledge to get out into the world where it can do good, we have to work with other sectors. Our tech transfer office is the bridge to those other sectors.鈥

William Platt can be reached at william.c.platt@dartmouth.edu.

Bill Platt